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Weight Loss Supplements Biography
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The appeal of losing weight quickly is hard to resist. But do weight-loss pills and products lighten anything but your wallet? And are they a safe option for weight loss? Here's a look at some over-the-counter weight-loss pills and what they will and won't do for you.
Over-the-counter doesn't mean risk-free

A number of weight-loss pills are available at your local drugstore, supermarket or health food store. Even more options are available online. Most haven't been proved effective, and some may be downright dangerous.

Dietary supplements and weight-loss aids aren't subject to the same rigorous standards as are prescription drugs. Thus, they can be sold with limited proof of effectiveness or safety. Once a product is on the market, however, the Food and Drug Administration (FDA) monitors its safety and can take action to ban or recall dangerous products. Indeed, the FDA has banned the sale of supplements containing ephedra and other ephedrine-like ingredients.
Check the facts before you buy

It's important to do your homework if you're thinking about trying over-the-counter weight-loss pills. Read labels and talk with your doctor or pharmacist. Also be sure to check the FDA website for alerts about safety concerns and product recalls.

The table shows common weight-loss pills and what the research shows about their effectiveness and safety.

If you're considering trying weight-loss pills, be sure to talk with your doctor, especially if you have health problems or take prescription drugs. Your doctor can provide support and advice on losing weight and can monitor your progress. Just as important, your doctor can talk with you about possible side effects and what to watch out for.

In addition, your doctor can help determine if weight-loss pills are likely to interact with any prescription drugs you take. Many weight-loss pills contain multiple ingredients, such as herbs, botanicals, vitamins, minerals, and even caffeine or laxatives. If you take prescription drugs — or herbal or dietary supplements — adding weight-loss pills to the mix can be tricky.
Despite the hype, no quick fixes

The makers of weight-loss pills would like you to believe that their products will miraculously solve your weight problems. But keep in mind that even if you take a weight-loss pill, you still have to eat fewer calories than your body uses in order to lose weight. And even if these products help you lose weight initially, you will probably have to keep taking them to keep the weight off, which may not be practical or safe.

The reality is that there's no magic bullet for losing weight. The most effective way to lose weight and keep it off is through lifestyle changes: Eat healthy, low-calorie foods, watch portion sizes and be physically active. It's not magic, but it works. Weight loss, in the context of medicine, health, or physical fitness, is a reduction of the total body mass, due to a mean loss of fluid, body fat or adipose tissue and/or lean mass, namely bone mineral deposits, muscle, tendon, and other connective tissue. It can occur unintentionally due to an underlying disease or can arise from a conscious effort to improve an actual or perceived overweight or obese state.

Unintentional weight loss may be a result of loss of fat, muscle atrophy, fluid loss or a combination of these.[1][2] It is generally regarded as a medical problem when at least 10% of a person's body weight has been lost in six months[1][3] or 5% in the last month.[4] Another criterion used for assessing weight that is too low is the body mass index (BMI).[5] However, even lesser amounts of weight loss can be a cause for serious concern in a frail elderly person.[6]

Unintentional weight loss can occur because of an inadequately nutritious diet relative to a person's energy needs (generally called malnutrition). Disease processes, changes in metabolism, hormonal changes, medications or other treatments, disease- or treatment-related dietary changes, or reduced appetite associated with a disease or treatment can also cause unintentional weight loss.[1][2][3][7][8][9] Poor nutrient utilization can lead to weight loss, and can be caused by fistulae in the gastrointestinal tract, diarrhea, drug-nutrient interaction, enzyme depletion and muscle atrophy.[3]

Continuing weight loss may deteriorate into wasting, a vaguely defined condition called cachexia.[6] Cachexia differs from starvation in part because it involves a systemic inflammatory response.[6] It is associated with poorer outcomes.[1][6][7] In the advanced stages of progressive disease, metabolism can change so that they lose weight even when they are getting what is normally regarded as adequate nutrition and the body cannot compensate. This leads to a condition called anorexia cachexia syndrome (ACS) and additional nutrition or supplementation is unlikely to help.[3] Symptoms of weight loss from ACS include severe weight loss from muscle rather than body fat, loss of appetite and feeling full after eating small amounts, nausea, anemia, weakness and fatigue.

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